Cell Therapy Overview

SCI results from motor vehicle accidents, falls, violence, or sports-related injuries. At the cellular level, mild contusion to the spinal cord causes massive neuronal and glial cell loss, demyelination, cavitation, and glial scarring. These pathological changes result in loss of sensory perception, distal motor paralysis, and severe functional impairment. There is no cure for SCI; however, functional improvement depends on the success of a combination of molecular, cellular, and rehabilitative physiotherapy. Autologous cellular therapy for SCI patients is attractive to augment axonal sparing, remyelination, and overcome the physical and chemical barriers for repair. Celvive, Inc. has developed a new approach, using a closed bag system to isolate specific adult stem cells from the patients' own bone marrow.